Andrey Tovchigrechko
Senior Ai Scientist, Molecular Design @Danaher
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WORK HISTORY
Senior Ai Scientist, Molecular Design @Danaher
In silico protein design with AI tools and tool development
EDUCATION
Moscow Institute of Physics and Technology
PhD, biophysics
Moscow Institute of Physics and Technology
M.Sc., applied mathematics &physics
SKILLS
ABOUT ANDREY TOVCHIGRECHKO
I am a computational biologist and technical team leader focused on immune receptor therapy development, with experience spanning TCR and antibody discovery, structural modeling, single-cell and NGS multiomics in oncology, autoimmunity and infectious diseasesMy recent work combines:• AI/ML for protein design and immune receptor–antigen prediction, including novel diffusion modeling approaches and LLM-based pipelines• Single-cell, amplicon, and spatial RNA-seq analysis for tumor-reactive TCR/BCR discoveryNGS and long-read algorithms and sequencing assay development for target discovery in mRNA vaccines and cell therapies• Bioinformatics systems design for clinical and preclinical genomics, including GxP-validated workflows and cloud-native architecture• Close collaboration with cancer immunologists in developing a bioinformatics-guided therapeutic platform in solid tumorsI’ve led cross-functional computational and sequencing teams, co-led a research department during organizational transition, and driven AI initiatives in a PI-like role while remaining technically hands-on.I’m now seeking Principal Scientist or Director-level roles — either as an individual contributor or a team leader — where I can continue innovating at the intersection of AI, structural biology, and/or immune receptor and target discovery from multi-omics sequencing.
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