Andrew Browne

About Andrew Browne

Translational bioinformatician with a Ph.D. in Neuroscience and 13 years of experience, specializing in multi-omic integration, AI/ML modeling, biomarker/classifier development, single cell biology, and immuno-oncology. Proven track record in developing robust disease models and integrating large-scale datasets to drive impactful discoveries in human health and drug development.

Experience

1. Senior Computational Biologist

   Stellaromics Inc.

   Jan 2026 — Present · Boston, MA, US

   Partner with neuroscience researchers and cross-functional internal teams to design spatial transcriptomics studies, define success criteria, and select appropriate analysis strategies.• QC and troubleshoot end-to-end spatial datasets (segmentation/cell calling, expression matrices, metadata integrity), diagnosing root causes and proposing practical fixes/workarounds.• Perform cell-type calling, clustering, and spatial domain identification using established single-cell/spatial workflows (e.g, Seurat/Scanpy) and bespoke analytical approaches.• Conduct differential expression and pathway/gene set analyses, connecting molecular signatures to neuroanatomy, disease models, and circuit-relevant hypotheses.• Apply advanced spatial analytics (e.g, co-localization, neighborhood/circuit-style connectivity metrics) to translate 3D spatial patterns into biologically meaningful insights.• Create and deliver clear scientific narratives (e.g. figures, slide decks, and written reports) tailored to experimental audiences and decision-making needs.• Support onboarding of new customer sites by guiding initial experiments, best practices, and analysis workflows, ensuring reproducible results and fast time-to-insight.• Provide structured, actionable feedback from real-world studies to improve analysis pipelines, QC metrics, and software UX, including testing/validating new features on customer-like datasets.• Build/maintain interactive dashboards and visualization tools for spatial and multi-omic interpretation, enabling rapid exploration of cell states, spatial organization, and biomarkers.• Collaborate on brain-region–specific panel strategy and contribute biological input to probe/panel refinement as needed to maximize interpretability and experimental power.

Education

• Ransom Everglades

  High School Diploma

  2000 — 2004

• Brown University

  Bachelor of Science, Neuroscience

  2004 — 2008

• Icahn School of Medicine at Mount Sinai

  Doctor of Philosophy - PhD, Neuroscience

  2011 — 2018