Amritlal Mandal

About Amritlal Mandal

Dr. Amritlal Mandal has made significant contributions bridging academic research and industrial innovation, impacting both biomedical science and clinical diagnostics. In academia, his pioneering research on sodium hydrogen exchangers (NHEs) has significantly advanced understanding of cellular pH regulation, particularly in ocular diseases such as glaucoma and cataracts. Additionally, his work on matrix metalloproteinases has deepened insights into cardiovascular disease and tissue remodeling, becoming foundational in these fields. With over 60 peer-reviewed publications and more than citations, Dr. Mandal’s research has influenced a broad spectrum of biomedical investigations. He has also demonstrated a strong commitment to mentoring junior scientists and leading complex research projects at top universities, helping to cultivate future scientific leaders.• In the industrial sector, Dr. Mandal has successfully translated his academic expertise into innovative diagnostic technologies. At Ventana Medical Systems (Roche Tissue Diagnostics), he led the development of advanced Class CDx assays. His expertise spans regulatory strategy, product development, and post-market surveillance, playing a key role in bringing life-saving diagnostic tools to patients. • Moreover, his experience in regulatory affairs, peer review and GXP including practice of quality documentation has helped maintain scientific rigor and accelerate the availability of precision diagnostics in clinical practice. Dr. Mandal’s dual impact in research and industry highlights his dedication to advancing science and improving healthcare.

Experience

1. Senior Scientist

   罗氏公司

   Mar 2026 — Present · Tucson, AZ, US

   Technical Lead for the project overseeing the development of Class DP CDx assay. Also supports RUO and Class I products.• Leads a dedicated team consisting of PhD level scientists and Masters/Bachelors level Research Associates. • Solves complex problems by offering creative solutions.• Takes great care fostering scientific and creative talents within the team by mentoring next generation scientists.• Responsible for on-time milestone deliverables for the product development.• Designs, plans, executes, and analyzes scientific studies while interpreting complex results per product.• Trains junior team members in a cross-functional environement.• Owns many PDP and regulatory documerntations. • Creates, reviews and provides SME level supports on many PDP documerntations. • Plays critical role in process development.• Troubleshoots and writes unique documents/reports for keeping the organization regulatory and audit compliant.• Collaborates with phrama partners on Class CDx and Drug co-development.• Deep knowledge of international product launch in compliance with country-specific local regulatory guidance.• Leads Post-Market Surveillance and Literature Review effort and report drafting to address customer complaints and recommends corrective and preventive actions for on-market IHC products

Education

• University of Calcutta

  BSc, Chemistry

  1992 — 1995

• University of Kalyani

  Ph.D., Biochemistry

  2000 — 2005

• Barisha High School

  Secondary, Mathematics, Physical Sciences, Life Sciences

  1987 — 1990

• Vivekananda college

  Higher Secondary, Science

• University of Calcutta

  MSc, Biochemistry

  1996 — 1998

Skills

• Cell
• Chemistry
• Elisa
• Physiology and Pharmacology
• Recombinant Dna Technology
• Flow Cytometry
• Molecular Genetics
• Characterization
• Immunofluorescence
• Transfection
• Biophysics
• Signal Transduction
• Rt-Pcr
• Tissue Culture
• Protein Chemistry
• Dna Sequencing
• Laboratory
• Assay Development
• Molecular Biology
• Fluorescence Microscopy
• Cell Signaling
• Confocal Microscopy
• Site-Directed Mutagenesis
• Proteomics
• Molecular Cloning
• Animal Models
• Immunoprecipitation
• Science
• Biochemistry
• Western Blotting
• Immunohistochemistry
• Qpcr
• Sequence Analysis
• Cell Biology
• Pcr
• Protein Purification
• Microbiology
• Purification
• Protein Expression
• Fplc