Amit Kalgutkar
Adjunct Professor @University Of Rhode Island College Of Pharmacy
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WORK HISTORY
Adjunct Professor @University Of Rhode Island College Of Pharmacy
Kingston, RI, US
EDUCATION
Vanderbilt University School of Medicine
Post-doctoral
Virginia Tech
PhD
University of Mumbai
M.Sc.
ABOUT AMIT KALGUTKAR
20 years experience as a \"Drug Hunter\" with over a dozen clinical candidates nominated in diverse therapeutic areas spanning allergy/respiratory, inflammation, obesity, atherosclerosis, osteoporosis, and diabetes. DM/PK Project Lead involved in the discovery/development of 3CLpro inhibitor PF-07••••32 (Nirmatrelvir) for the treatment of COVID-19 in combination with Ritonavir (PAXLOVID)DM/PK Lead involved in the discovery/advanced development of: Ertugliflozin (SGLT2 inhibitor), Danuglipron (Oral GLP-1 agonist), Clesacostat (ACC inhibitor).Authored over 180 peer reviewed publications, reviews and text book chapters in the fields of medicinal chemistry and drug metabolism. Book Editor for: Pharmacokinetics and Metabolism in Drug Design – 3rd Edition (Methods and Principles in Medicinal Chemistry)Reactive Drug Metabolites - Volume 55 (Methods and Principles in Medicinal Chemistry)Co-inventor on 8 patents in medicinal chemistry/drug design.Editorial board:Drug Metabolism and Disposition (ASPET)XenobioticsChemical Research in Toxicology (American Chemical Society)Specialties: Drug discovery, Mechanistic drug metabolism and pharmacokinetics, Chemical toxicology, Medicinal chemistry, and Chemical biology
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