Anthony Melvin Crasto Global Ambassador

About Anthony Melvin Crasto Global Ambassador

ADVISOR AFRICUREPHARMA, ROW2TECH ANAX IPCA ADVECT PROC GLENMARK NIPER-G, DeptPharma Min chem & Fert GovtofIndia, exGlenmark Sanofi exRPGGlobal Ambassador API & INT R&D, They tried to bury me but did not realize I was a seed, Ph.DOrg,ICT, India, a•••••••@gmail.com,+91••••••••80, 36yrs API, Multinationals, Process devl HoechstMRoussel(Sanofi), Searle,RPG, Innovassynth, Glenmark, basic rsh at SEARLE under Dr Nagarajan (Dir, Ciba), Techtransfer inplant. RPG, Bulk drug GMP (7 months) in Hoechst Marion Roussel(SANOFI), Custom syn in Innovasynth(SANDOZ, BASF ), exposure to natural pdts, drugs int,vet drugs, and some exposure in agro.speciality chemicals, flavours and fragrances, nutraceuticals and mettalocenes. ability to deliver pdts in the Prodn plant(35 API in career).Highlights1. Felt proud to spend millenium in plant2. Added personally a 25 kg NACN charge in a reactor at 2 in night, panoli, RPG.in 90\'decade, not to be TRIED3. Did not run away and controlled an exotherm in plant batch due to accidental addn of acid.Cl into NaCN rxn 4. Case when a thin film high vac distn exploded in a pilot plant in nasik for CBZ chem. UK, still able to despatch 100 kg material, Award london trip5. High vac. distilled 25 kg of drug int in the night using 3 pumps for a pilot plant trial intermediate, SANDOZ Basel, award bottleofwine from switzerland6. Personally worked after lab work in evenings with Dr Ralph Stapel,dir.Hoechst pilot plant at Mulund Mumbai, in 80\'​7. Assisted Head Asia pac, QA for TGA audit at Sanofi plant ankleshwar8 Slept for 3 hrs in morning in first aid room in Panoli during Deltamethrin process demo at panoli Gujarat, then noon 2 hrs at guest house during 6months campaign9 Reached Innovasynth lab in khopoli at 9morning from mumbai,100 km, using trucks,ricks after july monsoon deluge in Mumbai 200510 Got an opportunity to write a DMF in 90\'hoechst, Got a chance to work in tablets,large vol parenterals, inj, vaccines in Hoechst mulund plant11 Sixteen years with Glenmark in process research. patents, api, etcSpecialties: To carry out R&D, motivate, guide & lead a team of scientists,conduct lit.search,identify and execute new/novel routes for the synth,scale up from grams to kg levels in lab,conduct pilot trials/assist in prodn.upto ton levels. Carry out impty profiles and assist in dossier writing. To keep in mind IPR issues and draft patents, file DMFS in US/EU, file patents and contribute to intellectual property,Ability to develop novel routes for API,s, well versed with polymorphism issues. Qbd in process research,DOE

Experience

1. Advisor

   Advect Process Systems Ltd

   Sep 2024 — Present · IN

Education

• R.J.college, Ghatkopar, Bombay (Univ. of Bombay)

  M.Sc., Organic Chemistry

  1986

• St. Xavier`s high School, POWAI, MUMBAI

  S.S.C, GENERAL

  1970 — 1979

• Institute Of Chemical Technology

  Ph.D., ORGANIC CHEM.

  1987 — 1991

• R .J.college, Ghatkopar, Bombay (Univ. of Bombay)

  B.Sc, Chemistry

  1984

• R.J. COLLEGE GHATKOPAR MUMBAI

  HSC, SCAIENCE

  1979 — 1981

Skills

• Lc-Ms
• Plant Swern Oxidn at -90 Deg Cent, N2 Liq
• Hplc
• General Electronics
• Analytical Chemistry
• Business Management
• Writing
• Patents
• Organic Synthesis
• Therapeutic Drug Monitoring
• Intellectual Property
• Chromatography
• Organic Chemistry
• Computer Programming
• Regulatory
• Thin Films
• Patent Preparation
• Web Designing
• Process Research
• Nmr
• Validation
• Mass Spectrometry
• Industrial and Analytical Chemistry
• Stores Handling
• Uv
• Gc/Ms
• Nmr,Ir Inst--Operations--Udct
• Cgmp
• Thin Films High Vacuuum Distillation
• Microbiology
• Distillation
• Technology Transfer
• Electronics
• Uv-Vis
• Gc-Ms
• Fire Fighting
• Characterization
• Spectroscopy
• Dsc Instrument-Hoechst
• Ir