Alex J. Zhang

About Alex J. Zhang

HELP Therapeutics (HelpTx) is a global leader in iPSC-based cell therapies with a mission to redefine healthy aging. Our lead candidate, HiCM-188, is a novel iPSC-derived cardiomyocyte therapy for advanced heart failure. It has demonstrated a compelling safety and efficacy profile in multiple studies and is currently in Phase II trials in China, with US Phase I trials slated to begin in Q1 2026. By leveraging our unique combination of proprietary iPSC technology and an industrial-scale AI manufacturing platform, we are addressing degenerative diseases with significant unmet needs, including heart failure and age-related Macular Degeneration (AMD).

Experience

1. SVP, Head of International Business Development

   Help Therapeutics

   Jan 2023 — Present · Nanjing, CN

   Help Therapeutics (HelpTx) core technology platforms are built around allogeneic iPSC-derived cell therapy and a fully automated, AI-driven cell manufacturing system, enabling us to deliver highly effective and accessible therapies to a broader range of patients. Recent successes include securing US FDA and China NMPA clearances for our Investigational New Drug (IND) applications of HiCM-188 cell therapy to treat end-stage heart failure, marking significant milestones in our journey.Key Assets:* HiCM-188: iPSC-derived cardiomyocytes to treat advanced heart failure (HF) patients requiring CABG surgery (Phase I/II stage)* HiCM-288: iPSC-derived cardiomyocytes to treat dilated cardiomyopathy (DCM) via catheter delivery (IND-ready)* HiCM-388: iPSC-derived cardiomyocytes to treat acute myocardial infarction (AMI) via catheter delivery (Pre-clinical stage)* HiM 910: Mesenchymal stem cells (MSC) to treat osteoporosis patients with high risk of fractures (Phase I)* HELP Cell Foundry: Fully automated, AI-driven cell manufacturing platform for high quality, large scale cell productions

Education

• Shandong University

  BSc, Chemistry

• Cornell Johnson Graduate School of Management

  MBA, General Management

  2009 — 2010

• Texas A&M University

  PhD, Organic and Analytical Chemistry

Skills

• Drug Discovery
• Molecular Diagnostics
• Cross-Functional Team Leadership
• Marketing Strategy
• Strategy
• Start-Ups
• Management
• Business Development
• Lifesciences
• Product Development
• Life Sciences
• Business Strategy
• New Business Development
• Sales Management
• Biotechnology
• Pharmaceutical Industry
• Product Launch
• Product Launches
• Project Portfolio Management
• Product Management
• Entrepreneurship