Akshat Gupta

Bioinformatics Research Specialist Analyst @Upmc Hillman Cancer Center

Pittsburgh, PA, US

Processed TCGA RNA-seq files to identify intragenic rearrangements and gene fusions using EdgeR, limma, STAR, and Fusion-Zoom. Automated workflows on HPC with Slurm and Bash to enhance efficiency- Developed a scalable Nextflow pipeline for structural variant detection and tumor mutational burden calculation from WGS data, integrating GRIDSS, GATK, and MANTA- Mapped genomic coordinates across functional databases (TFBS, Cohesion, Enhancer) using GenomicRanges in R, enabling advanced regulatory network annotation- Trained wet lab scientists on HPC usage and RNA-seq analysis with DESeq2, improving team proficiency with computational tools- Collaborated with wet lab scientists to analyze experimental data, generate visualizations, and troubleshoot workflows, ensuring seamless integration of computational and experimental efforts.

Motilal Nehru National Institute Of Technology

Bachelor of Technology - BTech

Carnegie Mellon University

Master of Science - MS

Akshara International School, Pune

Senior Secondary (Class 12), Science