Angel Maldonado Lopez

About Angel Maldonado Lopez

Associate Director & Lab Head | Immuno-Oncology • Tumor Microenvironment • Advanced In Vitro SystemsI am a multidisciplinary discovery scientist with 14+ years in oncology and immuno-oncology, specializing in tumor microenvironment biology, immune–tumor interaction models, and innovative in vitro platforms that accelerate drug discovery.My scientific journey spans vascular biology, cardiology, ophthalmology, and oncology—giving me a uniquely adaptive, cross-disciplinary research mindset. Across my career at Takeda, I advanced from Senior Research Associate to Associate Director & Lab Head, driven by technical expertise, strategic thinking, and a commitment to mentoring and empowering scientific teams.As Lab Head, I lead a 10-scientist group focused on complex co-cultures, immune activation assays, 3D systems, MLRs, cytokine profiling, high-content imaging, and mechanism-of-action studies. I prioritize scientific rigor, operational excellence, and data integrity—ensuring reproducibility, traceability, and compliance with high-quality lab standards.I thrive at the intersection of innovation, leadership, and translational impact, bringing together biology, technology, and people to advance meaningful therapies.If you’re passionate about immuno-oncology or forward-looking scientific leadership, let’s connect.

Experience

1. Associate Director, Tumor Microenvironment Disruptors in Vitro Lab

   Takeda

   Nov 2025 — Present · Cambridge, MA, US

   Guide strategic research initiatives in tumor microenvironment biology, immunomodulation, and early oncology drug discovery.Drive scientific direction, resource prioritization, and platform expansion across key in vitro discovery systems.Partner with in vivo, translational, and computational groups to integrate multi-modal data and accelerate program advancement.Deliver scientific insights that inform mechanistic understanding, target validation, and portfolio decision-making.Shape team culture through mentorship, strategic guidance, and operational excellence initiatives.

Education

• Universidad de Puerto Rico

  B.S., Biology

  1997 — 2001

Skills

• Gel Electrophoresis
• Spectrophotometry
• Tissue Culture
• Histology
• Immunoprecipitation
• Cancer
• In Vitro
• Confocal Microscopy
• Dna
• Research
• Western Blotting
• Molecular Biology
• Fluorescence Microscopy
• Mutagenesis
• Pcr
• Immunocytochemistry
• Microsoft Office
• Molecular Cloning
• Animal Models
• Rt-Pcr
• Biochemistry
• Oncology
• Immunofluorescence
• Life Sciences
• Navision
• Dna Extraction
• Immunohistochemistry
• Qpcr
• Microscopy
• Elisa
• Fluorescence
• Rna Isolation
• Genotyping
• Physiology
• Cell Culture
• Screening
• Iwork
• Staining
• Cancer Research
• Sds-Page