Aaron Cranston

Director - Translational Research @Almac Group

Belfast, GB
MOBILE NUMBERS
+91 *********19

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WORK HISTORY

Apr 2024 — Present

Director - Translational Research @Almac Group

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Belfast, GB

Delivered high quality preclinical candidate selection activities in a matrix team environment. Clinical positioning and biomarker development. Leading IHC activities for late-stage lead op projects and adopting machine learning and AI approaches for digital pathology and biomarker development. Evaluating new/novel approaches to improve translational predictions and clinical positioning. Site audits and establishing procedures for delivering quality systems for preclinical safety, tox and efficacy projects. Increased breadth, depth and access to preclinical partners. Established and developed good partner relations. Delivered high quality work packages to aid project positioning, inform the clinical path and achieved successful asset out-licensing.

EDUCATION

1989 — 1996

Queen's University Belfast

B.Sc.(Hons), Ph.D., Genetics

SKILLS

R&DCns ModelsTarget IdentificationProject ManagementCROLifesciencesDrug DiscoveryCancer ModelsToxicologyBiotechnologyPharmacokineticsPharmacodynamicsGeneticsOrphan DrugsPharmacologyCell CultureImmunologyAssay DevelopmentTissue CultureTranslational MedicineGene TargetingCRO ManagementIn Vivo SkillsLine ManagementCellBiomarkersDrug DevelopmentCancerBioanalysisBiochemistryOncologyMolecular BiologyTarget ValidationLife SciencesOrphan DesignationPharmaceutical IndustryClinical DevelopmentIn VivoIn VitroTranslational Research

ABOUT AARON CRANSTON

Pre-clinical biologist with over 20 years\' experience in oncology, spanning a strong academic career in cancer genetics followed by a productive career in drug discovery and translational science in three successful small biotechs. Most proud of olaparib which continues to make a real difference to patient treatment, survival and quality of life.Specialties: Oncology, ophthalmology, CNS, metabolism, genetics, preclinical models, project management, establishing teams, drug discovery, translational research and asset commercialisation.

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Aaron Cranston — Director - Translational Research at Almac Group in Belfast, GB | Unifers