Aaditya Surya

Undergraduate Research Fellow @RIT Golisano College of Computing and Information Sciences

Rochester, NY, US

KC Lab is a computational biology research group at the Rochester Institute of Technology focused on applying machine learning and data-driven methods to understand protein structure, function, and evolution.At KC Lab, I conduct research on predicting N-linked glycosylation sites in archaeal proteins using protein language models (ESM-2, ProtT5, etc.) and large language model techniques. My work involves analyzing 5–10 million-entry mass spectrometry datasets and building robust pipelines to prepare large-scale data for model training. I design and train deep learning models for protein sequence classification, applying transfer learning, low-rank adaptation (LoRA), and full sequence-based window embeddings (FSWE) to adapt human-derived models for low-resource archaeal domains. I also generate custom sequence embeddings, optimize performance on imbalanced datasets, and develop evaluation sets tailored to archaeal proteins. Beyond classification, I explore extensions using structural data (e.g, AlphaFold outputs) to deepen insights into glycosylation and post-translational modifications, contributing to the broader understanding of protein evolution and biomedical research.

Lincoln School Nepal

High School Diploma

Bishop Mackenzie International School

Middle School Diploma

University of Southern California

Bachelor of Science - BS, Computer Science and Business Administration